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HomoloGene:38186. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   TXNIP,  H.sapiens
thioredoxin interacting protein
391 aa
   TXNIP,  P.troglodytes
thioredoxin interacting protein
391 aa
   TXNIP,  M.mulatta
thioredoxin interacting protein
391 aa
   TXNIP,  C.lupus
thioredoxin interacting protein
391 aa
   TXNIP,  B.taurus
thioredoxin interacting protein
391 aa
   Txnip,  M.musculus
thioredoxin interacting protein
396 aa
   Txnip,  R.norvegicus
thioredoxin interacting protein
394 aa
   txnip,  X.tropicalis
thioredoxin interacting protein
388 aa
   txnipa,  D.rerio
thioredoxin interacting protein a
400 aa
   txnipb,  D.rerio
thioredoxin interacting protein b
378 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Structure of the N-terminal domain of human thioredoxin-interacting protein.
Polekhina G, et al. Acta Crystallogr D Biol Crystallogr 69, 333-44 (2013).
Posttranslational regulation of thioredoxin-interacting protein.
Robinson KA, et al. J Mol Endocrinol 50, 59-71 (2013).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Arrestin_N (pfam00339)
  Arrestin (or S-antigen), N-terminal domain.
PBP2_LTTR_substrate (cl11398)
  The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily.
Arrestin_C (cl02844)
  Arrestin (or S-antigen), C-terminal domain.
Arrestin_N (cl19290)
  Arrestin (or S-antigen), N-terminal domain.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Txnip includes H.sapiens TXNIP and R.norvegicus Txnip.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (21 transcripts, 16 species)
Actinopterygii - bony fishes (16 transcripts, 12 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)




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