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HomoloGene:47948. Gene conserved in Amniota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   C4BPA,  H.sapiens
complement component 4 binding protein, alpha
    NP_000706.1
597 aa
   C4BPA,  P.troglodytes
complement component 4 binding protein, alpha
    XP_514156.2
597 aa
   C4BPA,  M.mulatta
complement component 4 binding protein, alpha
    XP_001082210.1
598 aa
   C4BPA,  C.lupus
complement component 4 binding protein, alpha
    XP_003434998.1
606 aa
   C4BPA,  B.taurus
complement component 4 binding protein, alpha
    NP_776677.1
610 aa
   C4bpa,  R.norvegicus
complement component 4 binding protein, alpha
    NP_036648.2
601 aa
   LOC419851,  G.gallus
complement component 4 binding protein, alpha chain
    NP_001028814.1
713 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Binding of the complement inhibitor C4b-binding protein to Lyme disease Borreliae.
Pietikäinen J, et al. Mol Immunol 47, 1299-305 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CCP (cl00043)
  Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system.
CCP (cl00043)
  SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 8 species)

 

 

 

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