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HomoloGene:1884. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NOV,  H.sapiens
nephroblastoma overexpressed
    NP_002505.1
357 aa
   NOV,  P.troglodytes
nephroblastoma overexpressed gene
    XP_001142595.1
357 aa
   NOV,  M.mulatta
nephroblastoma overexpressed gene
    XP_001097136.1
357 aa
   NOV,  C.lupus
nephroblastoma overexpressed gene
    XP_532317.3
353 aa
   NOV,  B.taurus
nephroblastoma overexpressed gene
    NP_001095852.1
346 aa
   Nov,  M.musculus
nephroblastoma overexpressed gene
    NP_035060.1
354 aa
   Nov,  R.norvegicus
nephroblastoma overexpressed
    NP_110495.1
351 aa
   NOV,  G.gallus
nephroblastoma overexpressed gene
    NP_990599.1
351 aa
   nov,  X.tropicalis
nephroblastoma overexpressed
    XP_002938019.1
344 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

CCN3 protein participates in bone regeneration as an inhibitory factor.
Matsushita Y, et al. J Biol Chem 288, 19973-85 (2013).
Temporal and spatial expression of CCN3 during retina development.
Laurent M, et al. Dev Neurobiol 72, 1363-75 (2012).
[Effects of prenatal exposure to lead on hippocampal nephroblastoma over-expressed gene expression of offspring].
Liu Q, et al. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 28, 181-5 (2010).
Prognostic relevance of CCN3 in Ewing sarcoma.
Perbal B, et al. Hum Pathol 40, 1479-86 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
VWC (cl02515)
  von Willebrand factor type C domain.
TSP_1 (pfam00090)
  Thrombospondin type 1 domain.
VWC (pfam00093)
  von Willebrand factor type C domain.
IGFBP (pfam00219)
  Insulin-like growth factor binding protein.
GHB_like (cl00070)
  Glycoprotein hormone beta chain homologues.
TSP_1 (cl15278)
  Thrombospondin type 1 domain.
IGFBP (cl02472)
  Insulin-like growth factor binding protein.
TSP_1 (cl15278)
  Thrombospondin type 1 domain.
DAN (cl17734)
  DAN domain.
VWC (cl17735)
  von Willebrand factor type C domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nov includes H.sapiens NOV and R.norvegicus Nov.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 9 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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