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HomoloGene:15775. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MLC1,  H.sapiens
megalencephalic leukoencephalopathy with subcortical cysts 1
    NP_631941.1
377 aa
   MLC1,  P.troglodytes
megalencephalic leukoencephalopathy with subcortical cysts 1
    XP_515212.3
389 aa
   MLC1,  M.mulatta
megalencephalic leukoencephalopathy with subcortical cysts 1
    XP_001111622.1
377 aa
   MLC1,  C.lupus
megalencephalic leukoencephalopathy with subcortical cysts 1
    XP_848790.2
373 aa
   MLC1,  B.taurus
megalencephalic leukoencephalopathy with subcortical cysts 1
    NP_001070420.1
378 aa
   Mlc1,  M.musculus
megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
    NP_573504.1
382 aa
   Mlc1,  R.norvegicus
megalencephalic leukoencephalopathy with subcortical cysts 1
    NP_001101575.1
406 aa
   MLC1,  G.gallus
megalencephalic leukoencephalopathy with subcortical cysts 1
    XP_004937559.1
379 aa
   mlc1,  X.tropicalis
megalencephalic leukoencephalopathy with subcortical cysts 1
    NP_001072921.1
377 aa
   mlc1,  D.rerio
megalencephalic leukoencephalopathy with subcortical cysts 1
    NP_001098409.1
391 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Megalencephalic leukoencephalopathy with subcortical cysts.



Publications
Articles associated with genes and sequences of this homology group.

Novel mutations of the MLC1 gene in Turkish patients.
Yüzbaşioğlu A, et al. Eur J Med Genet 54, 281-3 (2011).
Prenatal diagnosis of megalencephalic leukodystrophy.
Shukla P, et al. Prenat Diagn 28, 357-9 (2008).




Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mlc1 includes H.sapiens MLC1 and R.norvegicus Mlc1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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