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HomoloGene:20548. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MMP13,  H.sapiens
matrix metallopeptidase 13 (collagenase 3)
    NP_002418.1
471 aa
   MMP13,  P.troglodytes
matrix metallopeptidase 13 (collagenase 3)
    XP_001154361.1
471 aa
   MMP13,  M.mulatta
matrix metallopeptidase 13 (collagenase 3)
    XP_001098996.1
471 aa
   MMP13,  C.lupus
matrix metallopeptidase 13 (collagenase 3)
    XP_536598.3
496 aa
   MMP13,  B.taurus
matrix metallopeptidase 13 (collagenase 3)
    NP_776814.1
471 aa
   Mmp13,  M.musculus
matrix metallopeptidase 13
    NP_032633.1
472 aa
   Mmp13,  R.norvegicus
matrix metallopeptidase 13
    NP_598214.1
472 aa
   MMP13,  G.gallus
matrix metallopeptidase 13 (collagenase 3)
    XP_003640635.1
471 aa
   LOC100490019,  X.tropicalis
collagenase 3-like
    XP_002934971.1
472 aa
   mmp13b,  D.rerio
matrix metalloproteinase 13b
    XP_001345507.1
461 aa
   CELE_C31B8.8,  C.elegans
CELE_C31B8.8
    NP_503790.1
579 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Spondyloepimetaphyseal dysplasia, Missouri type.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PG_binding_1 (pfam01471)
  Putative peptidoglycan binding domain.
HX (cd00094)
  Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
PG_binding_1 (pfam01471)
  Putative peptidoglycan binding domain.
ZnMc (cl00064)
  Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mmp13 includes H.sapiens MMP13 and R.norvegicus Mmp13.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 10 species)
Actinopterygii - bony fishes (9 transcripts, 5 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (2 transcripts, 1 species)

 

 

 

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