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HomoloGene:20166. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ADORA2A,  H.sapiens
adenosine A2a receptor
    NP_000666.2
412 aa
   ADORA2A,  P.troglodytes
adenosine A2a receptor
    XP_003953896.1
412 aa
   ADORA2A,  M.mulatta
adenosine A2a receptor
    XP_001095636.1
409 aa
   ADORA2A,  C.lupus
adenosine A2a receptor
    NP_001003278.1
412 aa
   ADORA2A,  B.taurus
adenosine A2a receptor
    XP_005218339.1
401 aa
   Adora2a,  M.musculus
adenosine A2a receptor
    NP_033760.2
410 aa
   Adora2a,  R.norvegicus
adenosine A2a receptor
    NP_445746.3
410 aa
   ADORA2A,  G.gallus
adenosine A2a receptor
    XP_425280.2
436 aa
   adora2a,  X.tropicalis
adenosine A2a receptor
    NP_001106398.1
392 aa
   adora2aa,  D.rerio
adenosine A2a receptor a
    NP_001034904.1
442 aa
   adora2ab,  D.rerio
adenosine A2a receptor b
    NP_001035125.1
447 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Potential role of A2A adenosine receptor in traumatic optic neuropathy.
Ahmad S, et al. J Neuroimmunol 264, 54-64 (2013).
A2A adenosine receptors are up-regulated in lymphocytes from amyotrophic lateral sclerosis patients.
Vincenzi F, et al. Amyotroph Lateral Scler Frontotemporal Degener 14, 406-13 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Adora2a includes H.sapiens ADORA2A and R.norvegicus Adora2a.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 9 species)
Actinopterygii - bony fishes (3 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 3 species)

 

 

 

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