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HomoloGene:143. Gene conserved in Euarchontoglires Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   GP1BA,  H.sapiens
glycoprotein Ib (platelet), alpha polypeptide
652 aa
   GP1BA,  P.troglodytes
glycoprotein Ib (platelet), alpha polypeptide
694 aa
   LOC721584,  M.mulatta
platelet glycoprotein Ib alpha chain-like
496 aa
   Gp1ba,  M.musculus
glycoprotein 1b, alpha polypeptide
734 aa
   Gp1ba,  R.norvegicus
glycoprotein Ib (platelet), alpha polypeptide
717 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

von Willebrand disease, platelet-type.
Bernard-Soulier syndrome, type A.
Nonarteritic anterior ischemic optic neuropathy, susceptibility to.

Articles associated with genes and sequences of this homology group.

GPIb VNTR C/C genotype may predict embolic events in infective endocarditis.
Daga S, et al. J Heart Valve Dis 22, 133-41 (2013).
Glycoprotein Ib-alpha Kozak polymorphism in ischemic stroke.
Esen FI, et al. Neurol Res 34, 68-71 (2012).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
LRR_8 (pfam13855)
  Leucine rich repeat.
LRRCT (smart00082)
  Leucine rich repeat C-terminal domain.
LRRNT (cl02423)
  Leucine rich repeat N-terminal domain.
Mucin (pfam01456)
  Mucin-like glycoprotein.
PLRV_ORF5 (pfam01690)
  Potato leaf roll virus readthrough protein.
LRR_8 (pfam13855)
  Leucine rich repeat.
HC2 (cl19298)
  Histone H1-like nucleoprotein HC2.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gp1ba includes H.sapiens GP1BA and R.norvegicus Gp1ba.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (5 transcripts, 5 species)

Insecta - insects (1 transcript, 1 species)

Turbellaria - flatworms (1 transcript, 1 species)




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