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HomoloGene:37297. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

VDR,  H.sapiens
vitamin D (1,25- dihydroxyvitamin D3) receptor
NP_001017536.1
477 aa
VDR,  P.troglodytes
vitamin D (1,25- dihydroxyvitamin D3) receptor
XP_003313793.2
460 aa
VDR,  M.mulatta
vitamin D (1,25- dihydroxyvitamin D3) receptor
XP_001095385.2
434 aa
VDR,  C.lupus
vitamin D (1,25- dihydroxyvitamin D3) receptor
XP_005636977.1
427 aa
VDR,  B.taurus
vitamin D (1,25- dihydroxyvitamin D3) receptor
NP_001161404.1
426 aa
Vdr,  M.musculus
vitamin D receptor
NP_033530.2
422 aa
Vdr,  R.norvegicus
vitamin D (1,25- dihydroxyvitamin D3) receptor
NP_058754.1
423 aa
VDR,  G.gallus
vitamin D (1,25- dihydroxyvitamin D3) receptor
NP_990429.1
451 aa
vdr,  X.tropicalis
vitamin D (1,25- dihydroxyvitamin D3) receptor
XP_002935703.1
420 aa
vdra,  D.rerio
vitamin D receptor a
NP_570994.1
453 aa
vdrb,  D.rerio
vitamin D receptor b
NP_001153457.1
422 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
?Osteoporosis, involutional.
Rickets, vitamin D-resistant, type IIA.
Rickets, vitamin D-resistant, type IIB.



Publications
Articles associated with genes and sequences of this homology group.

The VDR gene FokI polymorphism and ovarian cancer risk.
Xu H, et al. Tumour Biol 34, 3309-16 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Vdr includes H.sapiens VDR and R.norvegicus Vdr.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (15 transcripts, 8 species)
Mammalia - mammals (10 transcripts, 10 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (7 transcripts, 6 species)
Arachnida - arachnids (3 transcripts, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

 

 

 

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