Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:1953. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PDE4B,  H.sapiens
phosphodiesterase 4B, cAMP-specific
    NP_001032417.1
721 aa
   PDE4B,  P.troglodytes
phosphodiesterase 4B, cAMP-specific
    XP_003949484.1
721 aa
   PDE4B,  M.mulatta
phosphodiesterase 4B, cAMP-specific
    XP_001091940.1
721 aa
   PDE4B,  C.lupus
phosphodiesterase 4B, cAMP-specific
    XP_536678.3
722 aa
   PDE4B,  B.taurus
phosphodiesterase 4B, cAMP-specific
    NP_001096016.1
721 aa
   Pde4b,  M.musculus
phosphodiesterase 4B, cAMP specific
    NP_062814.2
721 aa
   Pde4b,  R.norvegicus
phosphodiesterase 4B, cAMP specific
    NP_058727.2
721 aa
   PDE4B,  G.gallus
phosphodiesterase 4B, cAMP-specific
    NP_001026462.1
563 aa
   pde4c,  X.tropicalis
phosphodiesterase 4C, cAMP-specific
    XP_002934844.2
781 aa
   pde4ba,  D.rerio
phosphodiesterase 4B, cAMP-specific a
    XP_708955.2
713 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Association study of PDE4B with panic disorder in the Japanese population.
Otowa T, et al. Prog Neuropsychopharmacol Biol Psychiatry 35, 545-9 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PDEase_I (pfam00233)
  3'5'-cyclic nucleotide phosphodiesterase.
HDc (cl17215)
  Metal dependent phosphohydrolases with conserved 'HD' motif.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pde4b includes H.sapiens PDE4B and R.norvegicus Pde4b.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (22 transcripts, 8 species)
Mammalia - mammals (15 transcripts, 10 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)
Turbellaria - flatworms (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

 

 

 

Write to the Help Desk