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HomoloGene:2362. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SRP54,  H.sapiens
signal recognition particle 54kDa
    NP_003127.1
504 aa
   SRP54,  P.troglodytes
signal recognition particle 54kDa
    XP_001136048.1
504 aa
   SRP54,  M.mulatta
signal recognition particle 54kDa
    XP_001082531.1
504 aa
   SRP54,  C.lupus
signal recognition particle 54kDa
    NP_001003272.1
504 aa
   SRP54,  B.taurus
signal recognition particle 54kDa
    NP_001033290.1
504 aa
   Srp54a,  M.musculus
signal recognition particle 54A
    NP_036029.2
504 aa
   Srp54b,  M.musculus
signal recognition particle 54B
    NP_001093579.1
504 aa
   Srp54a,  R.norvegicus
signal recognition particle 54A
    NP_446323.1
504 aa
   SRP54,  G.gallus
signal recognition particle 54kDa
    XP_421238.1
504 aa
   srp54,  X.tropicalis
signal recognition particle 54kDa
    NP_988977.1
504 aa
   srp54,  D.rerio
signal recognition particle 54
    NP_957282.1
504 aa
   Srp54k,  D.melanogaster
Signal recognition particle protein 54k
    NP_523931.1
508 aa
   AgaP_AGAP004610,  A.gambiae
AgaP_AGAP004610
    XP_315212.2
504 aa
   F21D5.7,  C.elegans
F21D5.7
    NP_501507.1
496 aa
   SRP54,  S.cerevisiae
SRP54
    NP_015413.1
541 aa
   KLLA0D09020g,  K.lactis
KLLA0D09020g
    XP_453464.1
530 aa
   AGOS_AAR041W,  E.gossypii
AGOS_AAR041W
    NP_982582.2
514 aa
   srp54,  S.pombe
srp54
    NP_588209.1
522 aa
   MGG_05977,  M.oryzae
MGG_05977
    XP_003711822.1
510 aa
   NCU09696,  N.crassa
NCU09696
    XP_960643.1
511 aa
   AT1G48900,  A.thaliana
AT1G48900
    NP_564535.1
495 aa
   Os01g0772800,  O.sativa
Os01g0772800
    NP_001044395.1
496 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SRP_SPB (pfam02978)
  Signal peptide binding domain.
SRP_SPB (pfam02978)
  Signal peptide binding domain.
SRP54_N (cl03758)
  This entry represents the N-terminal helical bundle domain of the 54 kDa SRP54 component, a GTP-binding protein that interacts with the signal sequence when it emerges from the ribosome. SRP54 of the signal recognition particle has a three-domain structure: an N-terminal helical bundle domain, a GTPase domain, and the M-domain that binds the 7s RNA and also binds the signal sequence. The extreme C-terminal region is glycine-rich and lower in complexity and poorly conserved between species.
Fer4_NifH (cl17203)
  The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion.
AAA (cl18944)
  The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Srp54a includes H.sapiens SRP54 and R.norvegicus Srp54a.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 15 species)
Actinopterygii - bony fishes (13 transcripts, 10 species)
Ascidiacea - tunicates (7 transcripts, 3 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (15 transcripts, 12 species)
Arachnida - arachnids (3 transcripts, 2 species)
Malacostraca - crustaceans (2 transcripts, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (3 transcripts, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (50 transcripts, 30 species)
Liliopsida - monocots (15 transcripts, 9 species)
Coniferopsida - conifers (5 transcripts, 3 species)
Isoetopsida - club-mosses (3 transcripts, 1 species)
Bryopsida - mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 2 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (2 transcripts, 2 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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