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HomoloGene:23162. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PTBP2,  H.sapiens
polypyrimidine tract binding protein 2
    NP_067013.1
531 aa
   PTBP2,  P.troglodytes
polypyrimidine tract binding protein 2
    XP_001157727.2
531 aa
   PTBP2,  M.mulatta
polypyrimidine tract binding protein 2
    XP_001105316.2
536 aa
   PTBP2,  C.lupus
polypyrimidine tract binding protein 2
    XP_005621933.1
537 aa
   Ptbp2,  M.musculus
polypyrimidine tract binding protein 2
    NP_062423.1
532 aa
   Ptbp2,  R.norvegicus
polypyrimidine tract binding protein 2
    NP_001005555.1
531 aa
   PTBP2,  G.gallus
polypyrimidine tract binding protein 2
    XP_004936631.1
606 aa
   ptbp2,  X.tropicalis
polypyrimidine tract binding protein 2
    NP_001072479.1
531 aa
   ptbp2b,  D.rerio
polypyrimidine tract binding protein 2b
    NP_001093477.1
538 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

RNA looping by PTB: Evidence using FRET and NMR spectroscopy for a role in splicing repression.
Lamichhane R, et al. Proc Natl Acad Sci U S A 107, 4105-10 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RRM_SF (cl17169)
  RNA recognition motif (RRM) superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ptbp2 includes H.sapiens PTBP2 and R.norvegicus Ptbp2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (23 transcripts, 10 species)
Mammalia - mammals (15 transcripts, 12 species)
Aves - birds (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Liliopsida - monocots (1 transcript, 1 species)

 

 

 

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