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HomoloGene:23401. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PCDH15,  H.sapiens
protocadherin-related 15
    NP_001136241.1
1790 aa
   PCDH15,  P.troglodytes
protocadherin-related 15
    XP_507798.3
1765 aa
   PCDH15,  M.mulatta
protocadherin-related 15
    XP_002805772.1
1788 aa
   PCDH15,  C.lupus
protocadherin-related 15
    XP_003433494.1
1797 aa
   LOC100140108,  B.taurus
protocadherin-15-like
    XP_005225407.1
1789 aa
   Pcdh15,  M.musculus
protocadherin 15
    NP_001136214.1
1790 aa
   Pcdh15,  R.norvegicus
protocadherin 15
    NP_001258306.1
1791 aa
   PCDH15,  G.gallus
protocadherin-related 15
    NP_001038119.1
2192 aa
   pcdh15,  X.tropicalis
protocadherin-related 15
    XP_004916517.1
2147 aa
   pcdh15a,  D.rerio
protocadherin 15a
    NP_001012500.1
1796 aa
   pcdh15b,  D.rerio
protocadherin 15b
    NP_001012504.1
1907 aa
   Cad99C,  D.melanogaster
Cadherin 99C
    NP_001189311.1
1706 aa
   AgaP_AGAP002310,  A.gambiae
AgaP_AGAP002310
    XP_312660.5
1762 aa
   cdh-5,  C.elegans
cdh-5
    NP_501487.1
1306 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Usher syndrome, type 1F.
Deafness, autosomal recessive 23.



Publications
Articles associated with genes and sequences of this homology group.

The circling mutant Pcdh15roda is a new mouse model for hearing loss.
Torres AA, et al. Mutat Res 751-752, 29-35 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CA_like (cl15786)
  Cadherin repeat-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pcdh15 includes H.sapiens PCDH15 and R.norvegicus Pcdh15.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 8 species)
Actinopterygii - bony fishes (4 transcripts, 3 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (4 transcripts, 4 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)

 

 

 

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