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HomoloGene:55670. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   PLAU,  H.sapiens
plasminogen activator, urokinase
431 aa
   PLAU,  P.troglodytes
plasminogen activator, urokinase
431 aa
   PLAU,  M.mulatta
plasminogen activator, urokinase
430 aa
   PLAU,  C.lupus
plasminogen activator, urokinase
428 aa
   PLAU,  B.taurus
plasminogen activator, urokinase
433 aa
   Plau,  M.musculus
plasminogen activator, urokinase
433 aa
   Plau,  R.norvegicus
plasminogen activator, urokinase
432 aa
   PLAU,  G.gallus
plasminogen activator, urokinase
434 aa
   plaua,  D.rerio
plasminogen activator, urokinase a
402 aa
   plaub,  D.rerio
plasminogen activator, urokinase b
432 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

Alzheimer disease, late-onset, susceptibility to.

Articles associated with genes and sequences of this homology group.

Structural investigations of recombinant urokinase growth factor-like domain.
Beloglazova IB, et al. Biochemistry (Mosc) 78, 517-30 (2013).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Tryp_SPc (cd00190)
  Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
KR (cl00100)
  Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Plau includes H.sapiens PLAU and R.norvegicus Plau.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (13 transcripts, 12 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)




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