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HomoloGene:11785. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   POF1B,  H.sapiens
premature ovarian failure, 1B
    NP_079197.3
589 aa
   POF1B,  P.troglodytes
premature ovarian failure, 1B
    XP_529059.2
284 aa
   POF1B,  M.mulatta
premature ovarian failure, 1B
    XP_001083070.1
589 aa
   POF1B,  C.lupus
premature ovarian failure, 1B
    XP_549114.2
589 aa
   Pof1b,  M.musculus
premature ovarian failure 1B
    NP_853557.1
587 aa
   Pof1b,  R.norvegicus
premature ovarian failure 1B
    NP_001100404.1
587 aa
   POF1B,  G.gallus
premature ovarian failure, 1B
    XP_420252.4
594 aa
   pof1b,  X.tropicalis
premature ovarian failure, 1B
    NP_001037946.1
623 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Premature ovarian failure 2B.



Publications
Articles associated with genes and sequences of this homology group.

Spatial and temporal expression of POF1B, a gene expressed in epithelia.
Rizzolio F, et al. Gene Expr Patterns 7, 529-34 (2007).
X chromosome genes and premature ovarian failure.
Bione S & Toniolo D. Semin Reprod Med 18, 51-7 (2000).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Smc (COG1196)
  Chromosome segregation ATPases [Cell division and chromosome partitioning].
SMC_prok_B (TIGR02168)
  chromosome segregation protein SMC, common bacterial type.
SMC_prok_A (TIGR02169)
  chromosome segregation protein SMC, primarily archaeal type.
Lebercilin (pfam15619)
  Ciliary protein causing Leber congenital amaurosis disease.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pof1b includes H.sapiens POF1B and R.norvegicus Pof1b.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 8 species)

 

 

 

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