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HomoloGene:3659. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MMP9,  H.sapiens
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
    NP_004985.2
707 aa
   MMP9,  P.troglodytes
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
    XP_003317021.1
699 aa
   MMP9,  M.mulatta
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
    XP_001104871.1
707 aa
   MMP9,  C.lupus
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
    NP_001003219.1
704 aa
   MMP9,  B.taurus
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
    NP_777169.1
712 aa
   Mmp9,  M.musculus
matrix metallopeptidase 9
    NP_038627.1
730 aa
   Mmp9,  R.norvegicus
matrix metallopeptidase 9
    NP_112317.1
708 aa
   MMP9,  G.gallus
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
    NP_989998.1
686 aa
   mmp9,  X.tropicalis
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
    NP_001006843.1
670 aa
   LOC100494738,  X.tropicalis
matrix metalloproteinase-9-like
    XP_002932554.1
684 aa
   mmp9,  D.rerio
matrix metalloproteinase 9
    NP_998288.1
680 aa
   AT2G45040,  A.thaliana
AT2G45040
    NP_182030.1
342 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Lumbar disc herniation, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Matrix metalloproteinase-9 as a potential tumor marker in breast cancer.
Nanda DP, et al. J Environ Pathol Toxicol Oncol 32, 115-29 (2013).
Prognostic value of MMP-9 in ovarian cancer: a meta-analysis.
Li LN, et al. Asian Pac J Cancer Prev 14, 4107-13 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PT (pfam04886)
  PT repeat.
PG_binding_1 (pfam01471)
  Putative peptidoglycan binding domain.
HX (cd00094)
  Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
PG_binding_1 (pfam01471)
  Putative peptidoglycan binding domain.
ZnMc (cl00064)
  Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...
FN2 (cl09951)
  Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mmp9 includes H.sapiens MMP9 and R.norvegicus Mmp9.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 11 species)
Actinopterygii - bony fishes (9 transcripts, 9 species)
Amphibia - amphibians (5 transcripts, 2 species)
Aves - birds (3 transcripts, 2 species)

Arthropoda
Maxillopoda - crustaceans (2 transcripts, 1 species)

Streptophyta
Eudicotyledons - eudicots (2 transcripts, 2 species)

 

 

 

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