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HomoloGene:2900. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ZPR1,  H.sapiens
ZPR1 zinc finger
    NP_003895.1
459 aa
   ZNF259,  P.troglodytes
zinc finger protein 259
    XP_001152978.1
459 aa
   ZNF259,  C.lupus
zinc finger protein 259
    XP_850312.1
460 aa
   ZNF259,  B.taurus
zinc finger protein 259
    NP_001033593.1
459 aa
   Zfp259,  M.musculus
zinc finger protein 259
    NP_035882.1
459 aa
   Zfp259,  R.norvegicus
zinc finger protein 259
    NP_001131118.1
459 aa
   ZNF259,  G.gallus
zinc finger protein 259
    XP_003642643.1
447 aa
   znf259,  X.tropicalis
zinc finger protein 259
    NP_001017134.1
446 aa
   zpr1,  D.rerio
ZPR1 zinc finger
    NP_998273.1
441 aa
   Zpr1,  D.melanogaster
Zpr1
    NP_572532.1
457 aa
   AgaP_AGAP004417,  A.gambiae
AgaP_AGAP004417
    XP_562161.4
478 aa
   CELE_W03F9.1,  C.elegans
CELE_W03F9.1
    NP_503138.1
455 aa
   ZPR1,  S.cerevisiae
ZPR1
    NP_011727.3
486 aa
   KLLA0E16215g,  K.lactis
KLLA0E16215g
    XP_454680.1
492 aa
   AGOS_ACL137C,  E.gossypii
AGOS_ACL137C
    NP_983267.1
477 aa
   zpr1,  S.pombe
zpr1
    NP_594291.1
459 aa
   MGG_03238,  M.oryzae
MGG_03238
    XP_003716738.1
510 aa
   NCU08507,  N.crassa
NCU08507
    XP_963436.1
455 aa
   AT5G37340,  A.thaliana
AT5G37340
    NP_974856.1
498 aa
   AT5G22480,  A.thaliana
AT5G22480
    NP_197640.1
493 aa
   Os08g0471900,  O.sativa
Os08g0471900
    NP_001062017.1
501 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Deficiency of the zinc finger protein ZPR1 causes neurodegeneration.
Doran B, et al. Proc Natl Acad Sci U S A 103, 7471-5 (2006).
Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor.
Galcheva-Gargova Z, et al. Science 272, 1797-802 (1996).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-ZPR1 (pfam03367)
  ZPR1 zinc-finger domain.
zf-ZPR1 (cl19251)
  ZPR1 zinc-finger domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Zfp259 includes H.sapiens ZNF259 and R.norvegicus Zfp259.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (16 transcripts, 13 species)
Actinopterygii - bony fishes (10 transcripts, 8 species)
Ascidiacea - tunicates (3 transcripts, 3 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (10 transcripts, 10 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (32 transcripts, 23 species)
Liliopsida - monocots (11 transcripts, 8 species)
Coniferopsida - conifers (3 transcripts, 3 species)
Bryopsida - mosses (1 transcript, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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