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HomoloGene:4662. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ATG7,  H.sapiens
autophagy related 7
    NP_006386.1
703 aa
   ATG7,  P.troglodytes
autophagy related 7
    XP_003309672.2
685 aa
   ATG7,  M.mulatta
autophagy related 7
    XP_001088170.1
703 aa
   ATG7,  C.lupus
autophagy related 7
    XP_849849.2
704 aa
   ATG7,  B.taurus
autophagy related 7
    NP_001136439.1
703 aa
   Atg7,  M.musculus
autophagy related 7
    NP_001240646.1
741 aa
   Atg7,  R.norvegicus
autophagy related 7
    NP_001012097.1
698 aa
   ATG7,  G.gallus
autophagy related 7
    NP_001025763.1
709 aa
   atg7,  X.tropicalis
autophagy related 7
    NP_001123394.1
705 aa
   atg7,  D.rerio
ATG7 autophagy related 7 homolog (S. cerevisiae)
    XP_005172819.1
642 aa
   Atg7,  D.melanogaster
Autophagy-specific gene 7
    NP_611350.1
684 aa
   AgaP_AGAP010303,  A.gambiae
AgaP_AGAP010303
    XP_318213.4
682 aa
   atg-7,  C.elegans
atg-7
    NP_502064.1
647 aa
   ATG7,  S.cerevisiae
ATG7
    NP_012041.1
630 aa
   KLLA0A05137g,  K.lactis
KLLA0A05137g
    XP_451226.1
603 aa
   AGOS_AER298C,  E.gossypii
AGOS_AER298C
    NP_985155.1
625 aa
   atg7,  S.pombe
atg7
    NP_596084.1
649 aa
   MGG_07297,  M.oryzae
MGG_07297
    XP_003715525.1
714 aa
   NCU06672,  N.crassa
NCU06672
    XP_960919.1
699 aa
   APG7,  A.thaliana
APG7
    NP_568652.1
697 aa
   Os01g0614900,  O.sativa
Os01g0614900
    NP_001043569.1
1042 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Aβ secretion and plaque formation depend on autophagy.
Nilsson P, et al. Cell Rep 5, 61-9 (2013).
Paneth cells as a site of origin for intestinal inflammation.
Adolph TE, et al. Nature 503, 272-6 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NADB_Rossmann (cl09931)
  Rossmann-fold NAD(P)(+)-binding proteins.
E1_enzyme_family (cl17196)
  Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Atg7 includes H.sapiens ATG7 and R.norvegicus Atg7.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (19 transcripts, 12 species)
Actinopterygii - bony fishes (9 transcripts, 8 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (9 transcripts, 8 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (29 transcripts, 24 species)
Liliopsida - monocots (5 transcripts, 4 species)
Coniferopsida - conifers (2 transcripts, 1 species)
Bryopsida - mosses (1 transcript, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (2 transcripts, 1 species)

Ciliophora
Oligohymenophorea - ciliates (2 transcripts, 2 species)

 

 

 

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