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HomoloGene:925. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   PRDM1,  H.sapiens
PR domain containing 1, with ZNF domain
825 aa
   PRDM1,  P.troglodytes
PR domain containing 1, with ZNF domain
825 aa
   PRDM1,  M.mulatta
PR domain containing 1, with ZNF domain
825 aa
   PRDM1,  C.lupus
PR domain containing 1, with ZNF domain
822 aa
   PRDM1,  B.taurus
PR domain containing 1, with ZNF domain
828 aa
   Prdm1,  M.musculus
PR domain containing 1, with ZNF domain
823 aa
   Prdm1,  R.norvegicus
PR domain containing 1, with ZNF domain
824 aa
   PRDM1,  G.gallus
PR domain containing 1, with ZNF domain
812 aa
   prdm1,  X.tropicalis
PR domain containing 1, with ZNF domain
784 aa
   prdm1a,  D.rerio
PR domain containing 1a, with ZNF domain
776 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Conditional inactivation of Blimp1 in adult mice promotes increased bone mass.
Miyauchi Y, et al. J Biol Chem 287, 28508-17 (2012).
BLIMP1α, the master regulator of plasma cell differentiation is a tumor supressor gene in B cell lymphomas.
Vrzalikova K, et al. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 156, 1-6 (2012).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-H2C2_2 (pfam13465)
  Zinc-finger double domain.
SET (cl02566)
  SET domain.
zf-H2C2_2 (cl19539)
  Zinc-finger double domain.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Prdm1 includes H.sapiens PRDM1 and R.norvegicus Prdm1.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (10 transcripts, 8 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Amphibia - amphibians (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Echinoidea - sea urchins (3 transcripts, 2 species)

Arachnida - arachnids (1 transcript, 1 species)




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