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HomoloGene:8868. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ZEB2,  H.sapiens
zinc finger E-box binding homeobox 2
    NP_055610.1
1214 aa
   ZEB2,  P.troglodytes
zinc finger E-box binding homeobox 2
    XP_001158120.1
1214 aa
   ZEB2,  M.mulatta
zinc finger E-box binding homeobox 2
    XP_001093437.2
1254 aa
   ZEB2,  C.lupus
zinc finger E-box binding homeobox 2
    XP_005632021.1
1282 aa
   Zeb2,  M.musculus
zinc finger E-box binding homeobox 2
    NP_056568.2
1215 aa
   Zeb2,  R.norvegicus
zinc finger E-box binding homeobox 2
    NP_001028873.1
1215 aa
   ZEB2,  G.gallus
zinc finger E-box binding homeobox 2
    XP_422151.3
1214 aa
   zeb2,  X.tropicalis
zinc finger E-box binding homeobox 2
    XP_002936764.1
1214 aa
   zeb2b,  D.rerio
zinc finger E-box binding homeobox 2b
    NP_001232895.1
1219 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Mowat-Wilson syndrome.



Publications
Articles associated with genes and sequences of this homology group.

The transcription factor Zeb2 regulates signaling in mast cells.
Barbu EA, et al. J Immunol 188, 6278-86 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-H2C2_2 (pfam13465)
  Zinc-finger double domain.
zf-C2H2 (cl15478)
  Zinc finger, C2H2 type.
zf-C2H2 (pfam00096)
  Zinc finger, C2H2 type.
homeodomain (cl00084)
  Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
zf-H2C2_2 (cl19539)
  Zinc-finger double domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Zeb2 includes H.sapiens ZEB2 and R.norvegicus Zeb2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (22 transcripts, 13 species)
Actinopterygii - bony fishes (10 transcripts, 6 species)
Aves - birds (4 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

 

 

 

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