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HomoloGene:20253. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   OPRK1,  H.sapiens
opioid receptor, kappa 1
    NP_000903.2
380 aa
   OPRK1,  P.troglodytes
opioid receptor, kappa 1
    XP_003311840.2
498 aa
   OPRK1,  M.mulatta
opioid receptor, kappa 1
    XP_002805382.1
393 aa
   OPRK1,  C.lupus
opioid receptor, kappa 1
    XP_544080.2
380 aa
   OPRK1,  B.taurus
opioid receptor, kappa 1
    NP_001039945.1
380 aa
   Oprk1,  M.musculus
opioid receptor, kappa 1
    NP_001191300.1
380 aa
   Oprk1,  R.norvegicus
opioid receptor, kappa 1
    NP_058863.1
380 aa
   OPRK1,  G.gallus
opioid receptor, kappa 1
    XP_426087.2
381 aa
   oprk1,  X.tropicalis
opioid receptor, kappa 1
    XP_002934159.2
392 aa
   oprk1,  D.rerio
opioid receptor, kappa 1
    NP_878306.1
377 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Chemotype-selective modes of action of κ-opioid receptor agonists.
Vardy E, et al. J Biol Chem 288, 34470-83 (2013).
κ opioid regulation of anxiety-like behavior during acute ethanol withdrawal.
Valdez GR & Harshberger E. Pharmacol Biochem Behav 102, 44-7 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Oprk1 includes H.sapiens OPRK1 and R.norvegicus Oprk1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 8 species)
Actinopterygii - bony fishes (1 transcript, 1 species)

 

 

 

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