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HomoloGene:2677. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   OFD1,  H.sapiens
oral-facial-digital syndrome 1
    NP_003602.1
1012 aa
   OFD1,  P.troglodytes
oral-facial-digital syndrome 1
    XP_003953984.1
971 aa
   OFD1,  M.mulatta
oral-facial-digital syndrome 1
    XP_001098347.1
1013 aa
   OFD1,  C.lupus
oral-facial-digital syndrome 1
    XP_005641179.1
997 aa
   OFD1,  B.taurus
oral-facial-digital syndrome 1
    NP_001179566.2
1003 aa
   Ofd1,  M.musculus
oral-facial-digital syndrome 1 gene homolog (human)
    NP_803178.2
1019 aa
   Ofd1,  R.norvegicus
oral-facial-digital syndrome 1
    NP_001100431.1
1025 aa
   OFD1,  G.gallus
oral-facial-digital syndrome 1
    XP_416831.2
1012 aa
   ofd1,  X.tropicalis
oral-facial-digital syndrome 1
    XP_002933857.2
1010 aa
   ofd1,  D.rerio
oral-facial-digital syndrome 1
    NP_001004496.1
901 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Simpson-Golabi-Behmel syndrome, type 2.
Oral-facial-digital syndrome 1.



Publications
Articles associated with genes and sequences of this homology group.

Oral-Facial-Digital Syndrome Type I
Toriello HV, et al. (1993).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PTZ00449 (PTZ00449)
  104 kDa microneme/rhoptry antigen; Provisional.
SbcC (COG0419)
  ATPase involved in DNA repair [DNA replication, recombination, and repair].
Smc (COG1196)
  Chromosome segregation ATPases [Cell division and chromosome partitioning].
SMC_prok_B (TIGR02168)
  chromosome segregation protein SMC, common bacterial type.
PRK03918 (PRK03918)
  chromosome segregation protein; Provisional.
PriL (cl11970)
  Archaeal/eukaryotic core primase: Large subunit, PriL.
Med15 (pfam09606)
  ARC105 or Med15 subunit of Mediator complex non-fungal.
SprA-related (pfam12118)
  SprA-related family.
AAA_27 (pfam13514)
  AAA domain.
Rootletin (pfam15035)
  Ciliary rootlet component, centrosome cohesion.
Trypsin_2 (cl19303)
  Trypsin-like peptidase domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ofd1 includes H.sapiens OFD1 and R.norvegicus Ofd1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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