Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:3098. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

USP2,  H.sapiens
ubiquitin specific peptidase 2
NP_004196.4
605 aa
USP2,  P.troglodytes
ubiquitin specific peptidase 2
XP_001166112.1
605 aa
USP2,  M.mulatta
ubiquitin specific peptidase 2
XP_001105412.1
605 aa
USP2,  C.lupus
ubiquitin specific peptidase 2
XP_005619725.1
668 aa
USP2,  B.taurus
ubiquitin specific peptidase 2
NP_001039728.1
606 aa
Usp2,  M.musculus
ubiquitin specific peptidase 2
NP_058088.2
619 aa
Usp2,  R.norvegicus
ubiquitin specific peptidase 2
NP_446226.2
618 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

USP2a alters chemotherapeutic response by modulating redox.
Benassi B, et al. Cell Death Dis 4, e812 (2013).
Expression of USP2-69 in mesangial cells in vivo and in vitro.
Wang S, et al. Pathol Int 60, 184-92 (2010).
A genomic and functional inventory of deubiquitinating enzymes.
Nijman SM, et al. Cell 123, 773-86 (2005).
UBP41 is a proapoptotic ubiquitin-specific protease.
Gewies A & Grimm S. Cancer Res 63, 682-8 (2003).
Antagonistic regulation of myogenesis by two deubiquitinating enzymes, UBP45 and UBP69.
Park KC, et al. Proc Natl Acad Sci U S A 99, 9733-8 (2002).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Peptidase_C19 (cl02553)
  Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
UCH (pfam00443)
  Ubiquitin carboxyl-terminal hydrolase.
Peptidase_C19 (cl02553)
  Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Usp2 includes H.sapiens USP2 and R.norvegicus Usp2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (21 transcripts, 10 species)
Mammalia - mammals (9 transcripts, 9 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (5 transcripts, 2 species)
Turbellaria - flatworms (2 transcripts, 1 species)

Arthropoda
Insecta - insects (5 transcripts, 4 species)
Arachnida - arachnids (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)
Hydrozoa - hydrozoans (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (6 transcripts, 6 species)
Coniferopsida - conifers (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (3 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

Ascomycota
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

 

 

 

Write to the Help Desk