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HomoloGene:4544. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PPARD,  H.sapiens
peroxisome proliferator-activated receptor delta
    NP_006229.1
441 aa
   PPARD,  P.troglodytes
peroxisome proliferator-activated receptor delta
    XP_518905.2
441 aa
   PPARD,  M.mulatta
peroxisome proliferator-activated receptor delta
    XP_001116676.1
441 aa
   PPARD,  C.lupus
peroxisome proliferator-activated receptor delta
    NP_001041567.1
441 aa
   PPARD,  B.taurus
peroxisome proliferator-activated receptor delta
    NP_001077105.1
441 aa
   Ppard,  M.musculus
peroxisome proliferator activator receptor delta
    NP_035275.1
440 aa
   Ppard,  R.norvegicus
peroxisome proliferator-activated receptor delta
    NP_037273.2
440 aa
   PPARD,  G.gallus
peroxisome proliferator-activated receptor delta
    NP_990059.1
443 aa
   ppard,  X.tropicalis
peroxisome proliferator-activated receptor delta
    XP_002941448.1
387 aa
   pparda,  D.rerio
peroxisome proliferator-activated receptor delta a
    XP_699900.6
496 aa
   ppardb,  D.rerio
peroxisome proliferator-activated receptor delta b
    NP_571543.1
517 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

PPARβ/δ governs Wnt signaling and bone turnover.
Scholtysek C, et al. Nat Med 19, 608-13 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ppard includes H.sapiens PPARD and R.norvegicus Ppard.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (24 transcripts, 11 species)
Mammalia - mammals (11 transcripts, 11 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

 

 

 

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