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HomoloGene:4565. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   RRAS,  H.sapiens
related RAS viral (r-ras) oncogene homolog
218 aa
   RRAS,  P.troglodytes
related RAS viral (r-ras) oncogene homolog
218 aa
   RRAS,  M.mulatta
related RAS viral (r-ras) oncogene homolog
218 aa
   RRAS,  C.lupus
related RAS viral (r-ras) oncogene homolog
218 aa
   RRAS,  B.taurus
related RAS viral (r-ras) oncogene homolog
218 aa
   Rras,  M.musculus
Harvey rat sarcoma oncogene, subgroup R
218 aa
   Rras,  R.norvegicus
related RAS viral (r-ras) oncogene homolog
218 aa
   rras,  X.tropicalis
related RAS viral (r-ras) oncogene homolog
203 aa
   rras,  D.rerio
related RAS viral (r-ras) oncogene homolog
196 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

RRAS: A key regulator and an important prognostic biomarker in biliary atresia.
Zhao R, et al. World J Gastroenterol 17, 796-803 (2011).
The C-terminal end of R-Ras contains a focal adhesion targeting signal.
Furuhjelm J & Peränen J. J Cell Sci 116, 3729-38 (2003).
R-Ras promotes tumor growth of cervical epithelial cells.
Rincón-Arano H, et al. Cancer 97, 575-85 (2003).
Positive regulation of skeletal myogenesis by R-Ras.
Suzuki J, et al. Oncogene 19, 1138-46 (2000).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ras_like_GTPase (cl17170)
  Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases).

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rras includes H.sapiens RRAS and R.norvegicus Rras.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Echinoidea - sea urchins (1 transcript, 1 species)

Liliopsida - monocots (1 transcript, 1 species)




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