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HomoloGene:10321. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PDYN,  H.sapiens
prodynorphin
    NP_001177821.1
254 aa
   PDYN,  P.troglodytes
prodynorphin
    XP_003953712.1
254 aa
   PDYN,  M.mulatta
prodynorphin
    XP_001113720.1
253 aa
   PDYN,  C.lupus
prodynorphin
    XP_005634935.1
256 aa
   PDYN,  B.taurus
prodynorphin
    NP_776564.1
258 aa
   Pdyn,  M.musculus
prodynorphin
    NP_001273431.1
248 aa
   Pdyn,  R.norvegicus
prodynorphin
    NP_062247.2
248 aa
   PDYN,  G.gallus
prodynorphin
    XP_003642511.1
231 aa
   pdyn,  D.rerio
prodynorphin
    NP_001001831.1
252 aa
   LOC100536328,  D.rerio
proenkephalin-B-like
    XP_003201282.1
253 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Mutations in PDYN are not responsible for multiple system atrophy.
Fogel BL, et al. J Neurol 260, 927-8 (2013).
Dynorphin--still an extraordinarily potent opioid peptide.
Chavkin C. Mol Pharmacol 83, 729-36 (2013).
The frequency of spinocerebellar ataxia type 23 in a UK population.
Fawcett K, et al. J Neurol 260, 856-9 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Opiods_neuropep (pfam01160)
  Vertebrate endogenous opioids neuropeptide.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pdyn includes H.sapiens PDYN and R.norvegicus Pdyn.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 8 species)
Actinopterygii - bony fishes (2 transcripts, 1 species)

 

 

 

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