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HomoloGene:20659. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SLC7A2,  H.sapiens
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
    NP_001158243.1
698 aa
   SLC7A2,  P.troglodytes
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
    XP_001142615.2
658 aa
   SLC7A2,  M.mulatta
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
    XP_002805317.1
633 aa
   SLC7A2,  C.lupus
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
    XP_848421.1
658 aa
   SLC7A2,  B.taurus
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
    XP_005226081.1
698 aa
   Slc7a2,  M.musculus
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
    NP_001038205.1
658 aa
   Slc7a2,  R.norvegicus
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
    NP_001128158.1
658 aa
   SLC7A2,  G.gallus
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
    NP_001186031.1
655 aa
   slc7a2,  X.tropicalis
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
    XP_004911248.1
657 aa
   slc7a2,  D.rerio
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
    NP_001008584.1
640 aa
   CG7255,  D.melanogaster
CG7255
    NP_001036607.1
1063 aa
   AgaP_AGAP010563,  A.gambiae
AgaP_AGAP010563
    XP_314536.3
602 aa
   F23F1.6,  C.elegans
F23F1.6
    NP_493642.1
583 aa
   B0454.6,  C.elegans
B0454.6
    NP_494428.1
585 aa
   C50D2.2,  C.elegans
C50D2.2
    NP_493662.1
589 aa
   CAT3,  A.thaliana
CAT3
    NP_198510.2
609 aa
   CAT2,  A.thaliana
CAT2
    NP_849822.1
635 aa
   Os12g0623500,  O.sativa
Os12g0623500
    NP_001067309.1
621 aa
   Os03g0654400,  O.sativa
Os03g0654400
    NP_001050796.1
639 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

L-arginine uptake by cationic amino acid transporter 2 is essential for colonic epithelial cell restitution.
Singh K, et al. Am J Physiol Gastrointest Liver Physiol 302, G1061-73 (2012).
Molecular cloning and characterization of the chicken cationic amino acid transporter-2 gene.
Humphrey BD, et al. Comp Biochem Physiol B Biochem Mol Biol 150, 301-11 (2008).
Cationic amino acid transporter 2 regulates inflammatory homeostasis in the lung.
Rothenberg ME, et al. Proc Natl Acad Sci U S A 103, 14895-900 (2006).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
2A0303 (TIGR00906)
  cationic amino acid transport permease.
AA_permease_C (pfam13906)
  C-terminus of AA_permease.
Spore_permease (cl15802)
  Spore germination protein.
AA_permease_C (pfam13906)
  C-terminus of AA_permease.
Aa_trans (cl17468)
  Transmembrane amino acid transporter protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slc7a2 includes H.sapiens SLC7A2 and R.norvegicus Slc7a2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 8 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Insecta - insects (8 transcripts, 6 species)

Nematoda
Chromadorea - nematodes (4 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (14 transcripts, 8 species)
Liliopsida - monocots (3 transcripts, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

 

 

 

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