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HomoloGene:48483. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SYN1,  H.sapiens
synapsin I
    NP_008881.2
705 aa
   SYN1,  C.lupus
synapsin I
    XP_003435552.1
704 aa
   SYN1,  B.taurus
synapsin I
    NP_776616.1
706 aa
   Syn1,  M.musculus
synapsin I
    NP_038708.3
706 aa
   Syn1,  R.norvegicus
synapsin I
    NP_062006.1
704 aa
   LOC100158514,  X.tropicalis
uncharacterized LOC100158514
    NP_001121423.1
656 aa
   syn1,  D.rerio
synapsin I
    NP_001119909.1
670 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Epilepsy, X-linked, with variable learning disabilities and behavior disorders.



Publications
Articles associated with genes and sequences of this homology group.

Hispidulin inhibits the release of glutamate in rat cerebrocortical nerve terminals.
Lin TY, et al. Toxicol Appl Pharmacol 263, 233-43 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Synapsin_C (pfam02750)
  Synapsin, ATP binding domain.
Synapsin (pfam02078)
  Synapsin, N-terminal domain.
Synapsin_N (pfam10581)
  Synapsin N-terminal.
ATP-grasp_4 (cl03087)
  ATP-grasp domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Syn1 includes H.sapiens SYN1 and R.norvegicus Syn1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 9 species)
Amphibia - amphibians (2 transcripts, 2 species)
Actinopterygii - bony fishes (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

 

 

 

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