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HomoloGene:12938. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   GRIP1,  H.sapiens
glutamate receptor interacting protein 1
1076 aa
   GRIP1,  P.troglodytes
glutamate receptor interacting protein 1
1076 aa
   GRIP1,  M.mulatta
glutamate receptor interacting protein 1
1076 aa
   GRIP1,  C.lupus
glutamate receptor interacting protein 1
1203 aa
   GRIP1,  B.taurus
glutamate receptor interacting protein 1
597 aa
   Grip1,  M.musculus
glutamate receptor interacting protein 1
1060 aa
   Grip1,  R.norvegicus
glutamate receptor interacting protein 1
1112 aa
   GRIP1,  G.gallus
glutamate receptor interacting protein 1
1106 aa
   grip1,  X.tropicalis
glutamate receptor interacting protein 1
1084 aa
   grip1,  D.rerio
glutamate receptor interacting protein 1
1143 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Mutations in GRIP1 cause Fraser syndrome.
Vogel MJ, et al. J Med Genet 49, 303-6 (2012).
Differential roles of GRIP1a and GRIP1b in AMPA receptor trafficking.
Hanley LJ & Henley JM. Neurosci Lett 485, 167-72 (2010).
No association of GRIP1 gene polymorphisms with schizophrenia in Chinese population.
Tsai SJ, et al. Prog Neuropsychopharmacol Biol Psychiatry 31, 752-5 (2007).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RPA_2b-aaRSs_OBF_like (cl09930)
  Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.
PDZ (cl00117)
  PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Grip1 includes H.sapiens GRIP1 and R.norvegicus Grip1.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (14 transcripts, 8 species)
Actinopterygii - bony fishes (6 transcripts, 4 species)
Ascidiacea - tunicates (4 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)

Insecta - insects (3 transcripts, 2 species)

Echinoidea - sea urchins (2 transcripts, 1 species)




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