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HomoloGene:533. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   FASLG,  H.sapiens
Fas ligand (TNF superfamily, member 6)
    NP_000630.1
281 aa
   FASLG,  P.troglodytes
Fas ligand (TNF superfamily, member 6)
    XP_524967.2
280 aa
   FASLG,  M.mulatta
Fas ligand (TNF superfamily, member 6)
    NP_001028010.1
280 aa
   FASLG,  C.lupus
Fas ligand (TNF superfamily, member 6)
    XP_854009.1
286 aa
   FASLG,  B.taurus
Fas ligand (TNF superfamily, member 6)
    NP_001092329.1
277 aa
   Fasl,  M.musculus
Fas ligand (TNF superfamily, member 6)
    NP_034307.1
279 aa
   Faslg,  R.norvegicus
Fas ligand (TNF superfamily, member 6)
    NP_037040.1
278 aa
   FASLG,  G.gallus
Fas ligand (TNF superfamily, member 6)
    NP_001026730.1
253 aa
   faslg,  X.tropicalis
Fas ligand (TNF superfamily, member 6)
    XP_002934199.2
258 aa
   faslg,  D.rerio
Fas ligand (TNF superfamily, member 6)
    NP_001036166.1
268 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Systemic lupus erythematosus, susceptibility.



Publications
Articles associated with genes and sequences of this homology group.

Effects of FasL expression in oral squamous cell cancer.
Fang L, et al. Asian Pac J Cancer Prev 14, 281-5 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TNF (cl00147)
  Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...
GspL_C (cl14909)
  GspL periplasmic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fasl includes H.sapiens FASLG and R.norvegicus Faslg.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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