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HomoloGene:3722. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   XBP1,  H.sapiens
X-box binding protein 1
    NP_001073007.1
376 aa
   XBP1,  C.lupus
X-box binding protein 1
    XP_854633.3
388 aa
   XBP1,  B.taurus
X-box binding protein 1
    NP_001258666.1
376 aa
   Xbp1,  M.musculus
X-box binding protein 1
    NP_001258659.1
371 aa
   Xbp1,  R.norvegicus
X-box binding protein 1
    NP_001258660.1
371 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Bipolar disorder, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Multiple myeloma Leu167Ile (c.499C>A) mutation prevents XBP1 mRNA splicing.
Hong SY & Hagen T. Br J Haematol 161, 898-901 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
B_zip1 (cl02576)
  basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Xbp1 includes H.sapiens XBP1 and R.norvegicus Xbp1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (19 transcripts, 13 species)
Actinopterygii - bony fishes (12 transcripts, 9 species)
Cephalochordata - lancelets (3 transcripts, 1 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Arthropoda
Arachnida - arachnids (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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