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HomoloGene:34139. Gene conserved in Tetrapoda Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   DIDO1,  H.sapiens
death inducer-obliterator 1
2240 aa
   DIDO1,  P.troglodytes
death-inducer obliterator 1-like
1459 aa
   DIDO1,  M.mulatta
death inducer-obliterator 1
2250 aa
   DIDO1,  C.lupus
death inducer-obliterator 1
2212 aa
   DIDO1,  B.taurus
death inducer-obliterator 1
2196 aa
   Dido1,  M.musculus
death inducer-obliterator 1
2256 aa
   Dido1,  R.norvegicus
death inducer-obliterator 1
2258 aa
   DIDO1,  G.gallus
death inducer-obliterator 1
2493 aa
   dido1,  X.tropicalis
death inducer-obliterator 1
2281 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Dido3 PHD modulates cell differentiation and division.
Gatchalian J, et al. Cell Rep 4, 148-58 (2013).
DIO-1 is a gene involved in onset of apoptosis in vitro, whose misexpression disrupts limb development.
García-Domingo D, et al. Proc Natl Acad Sci U S A 96, 7992-7 (1999).
CSE1L, DIDO1 and RBM39 in colorectal adenoma to carcinoma progression.
Sillars-Hardebol AH, et al. Cell Oncol (Dordr) 35, 293-300 (2012).
[Mechanism of gambogic acid-induced apoptosis in Raji cells].
Wang Y, et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 17, 88-91 (2009).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PHD (pfam00628)
SPOC (pfam07744)
  SPOC domain.
TNG2 (COG5034)
  Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics].
PRK07764 (PRK07764)
  DNA polymerase III subunits gamma and tau; Validated.
ARS2 (pfam04959)
  Arsenite-resistance protein 2.
SPOC (pfam07744)
  SPOC domain.
DUF3315 (cl02275)
  Domain of unknown function (DUF3315).
TFIIS_M (cl02637)
  Transcription factor S-II (TFIIS), central domain.
PHD (cl17445)

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Dido1 includes H.sapiens DIDO1 and R.norvegicus Dido1.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (15 transcripts, 10 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Hydrozoa - hydrozoans (1 transcript, 1 species)

Echinoidea - sea urchins (1 transcript, 1 species)




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