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HomoloGene:7762. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   FOXA2,  H.sapiens
forkhead box A2
    NP_710141.1
457 aa
   FOXA2,  M.mulatta
forkhead box A2
    XP_001094972.1
457 aa
   FOXA2,  C.lupus
forkhead box A2
    XP_542865.2
468 aa
   FOXA2,  B.taurus
forkhead box A2
    XP_002692206.2
446 aa
   Foxa2,  M.musculus
forkhead box A2
    NP_034576.2
459 aa
   Foxa2,  R.norvegicus
forkhead box A2
    NP_036875.1
458 aa
   FOXA2,  G.gallus
forkhead box A2
    NP_990101.1
438 aa
   foxa2,  X.tropicalis
forkhead box A2
    NP_989423.1
434 aa
   foxa2,  D.rerio
forkhead box A2
    NP_571024.1
409 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Foxa2 regulates leukotrienes to inhibit Th2-mediated pulmonary inflammation.
Tang X, et al. Am J Respir Cell Mol Biol 49, 960-70 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Fork_head_N (pfam08430)
  Forkhead N-terminal region.
HNF_C (pfam09354)
  HNF3 C-terminal domain.
FH (cl00061)
  Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA ...
Fork_head_N (pfam08430)
  Forkhead N-terminal region.
HNF_C (pfam09354)
  HNF3 C-terminal domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Foxa2 includes H.sapiens FOXA2 and R.norvegicus Foxa2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (8 transcripts, 6 species)
Mammalia - mammals (7 transcripts, 7 species)
Ascidiacea - tunicates (5 transcripts, 3 species)
Amphibia - amphibians (5 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 3 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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