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HomoloGene:49153. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   F8,  H.sapiens
coagulation factor VIII, procoagulant component
    NP_000123.1
2351 aa
   F8,  P.troglodytes
coagulation factor VIII, procoagulant component
    XP_003317837.1
2351 aa
   LOC100424151,  M.mulatta
coagulation factor VIII-like
    XP_002806506.1
2152 aa
   F8,  C.lupus
coagulation factor VIII, procoagulant component
    NP_001003212.1
2343 aa
   F8,  B.taurus
coagulation factor VIII, procoagulant component
    NP_001138980.1
2323 aa
   F8,  M.musculus
coagulation factor VIII
    NP_032003.2
2319 aa
   F8,  R.norvegicus
coagulation factor VIII, procoagulant component
    NP_899160.1
2258 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hemophilia A.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FA58C (cl19067)
  Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
Cupredoxin (cl19115)
  Cupredoxin superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus F8 includes H.sapiens F8 and R.norvegicus F8.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 8 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Aves - birds (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

 

 

 

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