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HomoloGene:31368. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   XRCC1,  H.sapiens
X-ray repair complementing defective repair in Chinese hamster cells 1
    NP_006288.2
633 aa
   XRCC1,  P.troglodytes
X-ray repair complementing defective repair in Chinese hamster cells 1
    XP_001156934.3
742 aa
   XRCC1,  M.mulatta
X-ray repair complementing defective repair in Chinese hamster cells 1
    XP_001100256.2
617 aa
   XRCC1,  C.lupus
X-ray repair complementing defective repair in Chinese hamster cells 1
    XP_533653.3
629 aa
   XRCC1,  B.taurus
X-ray repair complementing defective repair in Chinese hamster cells 1
    XP_005219459.1
656 aa
   Xrcc1,  M.musculus
X-ray repair complementing defective repair in Chinese hamster cells 1
    NP_033558.3
631 aa
   Xrcc1,  R.norvegicus
X-ray repair complementing defective repair in Chinese hamster cells 1
    NP_445887.1
631 aa
   xrcc1,  X.tropicalis
X-ray repair complementing defective repair in Chinese hamster cells 1
    XP_002939185.2
652 aa
   xrcc1,  D.rerio
X-ray repair complementing defective repair in Chinese hamster cells 1
    NP_001003988.1
615 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Association of XRCC1 gene polymorphisms with breast cancer susceptibility in Saudi patients.
Al Mutairi FM, et al. Asian Pac J Cancer Prev 14, 3809-13 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ebola_NP (pfam05505)
  Ebola nucleoprotein.
XRCC1_N (pfam01834)
  XRCC1 N terminal domain.
XRCC1_N (pfam01834)
  XRCC1 N terminal domain.
Nha1_C (pfam08619)
  Alkali metal cation/H+ antiporter Nha1 C terminus.
BRCT (cl00038)
  Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo/hetero BRCT multimers, BRCT-non-BRCT interactions, and interactions within DNA strand breaks.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Xrcc1 includes H.sapiens XRCC1 and R.norvegicus Xrcc1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 10 species)
Actinopterygii - bony fishes (8 transcripts, 7 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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