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HomoloGene:49320. Gene conserved in Amniota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TNFRSF13B,  H.sapiens
tumor necrosis factor receptor superfamily, member 13B
    NP_036584.1
293 aa
   TNFRSF13B,  P.troglodytes
tumor necrosis factor receptor superfamily, member 13B
    XP_001161361.2
293 aa
   TNFRSF13B,  M.mulatta
tumor necrosis factor receptor superfamily, member 13B
    XP_001088700.2
247 aa
   TNFRSF13B,  C.lupus
tumor necrosis factor receptor superfamily, member 13B
    XP_005620235.1
295 aa
   Tnfrsf13b,  M.musculus
tumor necrosis factor receptor superfamily, member 13b
    NP_067324.1
249 aa
   TNFRSF13B,  G.gallus
tumor necrosis factor receptor superfamily, member 13B
    NP_001091006.1
259 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Common variable immunodeficiency.
Immunoglobulin A deficiency.



Publications
Articles associated with genes and sequences of this homology group.

Heterozygous alterations of TNFRSF13B/TACI in tonsillar hypertrophy and sarcoidosis.
Speletas M, et al. Clin Dev Immunol 2013, 532437 (2013).
TACI mutations and impaired B-cell function in subjects with CVID and healthy heterozygotes.
Martinez-Gallo M, et al. J Allergy Clin Immunol 131, 468-76 (2013).
The impact of TACI mutations: from hypogammaglobulinemia in infancy to autoimmunity in adulthood.
Barroeta Seijas AB, et al. Int J Immunopathol Pharmacol 25, 407-14 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TACI-CRD2 (pfam09305)
  TACI, cysteine-rich domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tnfrsf13b includes H.sapiens TNFRSF13B and R.norvegicus Tnfrsf13b.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (4 transcripts, 4 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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