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HomoloGene:37750. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NR2E1,  H.sapiens
nuclear receptor subfamily 2, group E, member 1
    NP_003260.1
385 aa
   NR2E1,  P.troglodytes
nuclear receptor subfamily 2, group E, member 1
    XP_527467.2
385 aa
   NR2E1,  M.mulatta
nuclear receptor subfamily 2, group E, member 1
    XP_001094659.1
385 aa
   NR2E1,  C.lupus
nuclear receptor subfamily 2, group E, member 1
    XP_532253.2
385 aa
   NR2E1,  B.taurus
nuclear receptor subfamily 2, group E, member 1
    NP_001179582.1
385 aa
   Nr2e1,  M.musculus
nuclear receptor subfamily 2, group E, member 1
    NP_689415.1
385 aa
   Nr2e1,  R.norvegicus
nuclear receptor subfamily 2, group E, member 1
    NP_001106668.1
385 aa
   NR2E1,  G.gallus
nuclear receptor subfamily 2, group E, member 1
    NP_990501.1
385 aa
   nr2e1,  X.tropicalis
nuclear receptor subfamily 2, group E, member 1
    XP_002937209.2
386 aa
   nr2e1,  D.rerio
nuclear receptor subfamily 2, group E, member 1
    NP_001003608.1
396 aa
   dsf,  D.melanogaster
dissatisfaction
    NP_477140.1
691 aa
   nhr-67,  C.elegans
nhr-67
    NP_502094.1
416 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Absence of NR2E1 mutations in patients with aniridia.
Corso-Díaz X, et al. Mol Vis 18, 2770-82 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nr2e1 includes H.sapiens NR2E1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 3 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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