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HomoloGene:31426. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   USF1,  H.sapiens
upstream transcription factor 1
310 aa
   USF1,  P.troglodytes
upstream transcription factor 1
310 aa
   USF1,  M.mulatta
upstream transcription factor 1
366 aa
   USF1,  C.lupus
upstream transcription factor 1
310 aa
   USF1,  B.taurus
upstream transcription factor 1
310 aa
   Usf1,  M.musculus
upstream transcription factor 1
310 aa
   Usf1,  R.norvegicus
upstream transcription factor 1
310 aa
   USF1,  G.gallus
upstream transcription factor 1
310 aa
   usf1,  D.rerio
upstream transcription factor 1
309 aa
   usf1l,  D.rerio
upstream transcription factor 1, like
283 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

hyperlipidemia, familial combined.
Hyperlipidemia, familial combined, susceptibility to.

Articles associated with genes and sequences of this homology group.

Role of the USF1 transcription factor in diabetic kidney disease.
Sanchez AP, et al. Am J Physiol Renal Physiol 301, F271-9 (2011).
[Regulation of osteopontin expression in odontoblasts by upstream stimulatory factor 1].
Wu LA, et al. Zhonghua Kou Qiang Yi Xue Za Zhi 42, 663-4 (2007).
Association analysis of allelic variants of USF1 in coronary atherosclerosis.
Kristiansson K, et al. Arterioscler Thromb Vasc Biol 28, 983-9 (2008).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HLH (cl00081)
  Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Usf1 includes H.sapiens USF1 and R.norvegicus Usf1.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (14 transcripts, 13 species)
Ascidiacea - tunicates (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Insecta - insects (4 transcripts, 3 species)

Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)




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