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HomoloGene:55964. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PRKG1,  H.sapiens
protein kinase, cGMP-dependent, type I
    NP_006249.1
686 aa
   PRKG1,  P.troglodytes
protein kinase, cGMP-dependent, type I
    XP_001162858.1
686 aa
   PRKG1,  M.mulatta
protein kinase, cGMP-dependent, type I
    XP_001099460.1
686 aa
   PRKG1,  C.lupus
protein kinase, cGMP-dependent, type I
    XP_851997.2
671 aa
   PRKG1,  B.taurus
protein kinase, cGMP-dependent, type I
    NP_776861.1
671 aa
   Prkg1,  M.musculus
protein kinase, cGMP-dependent, type I
    NP_001013855.1
671 aa
   Prkg1,  R.norvegicus
protein kinase, cGMP-dependent, type 1
    NP_001099201.3
671 aa
   PRKG1,  G.gallus
protein kinase, cGMP-dependent, type I
    XP_003641507.2
742 aa
   LOC100494278,  X.tropicalis
cGMP-dependent protein kinase 1-like
    XP_002935474.2
685 aa
   prkg1a,  D.rerio
protein kinase, cGMP-dependent, type Ia
    NP_957324.1
667 aa
   for,  D.melanogaster
foraging
    NP_477488.1
742 aa
   AgaP_AGAP008863,  A.gambiae
AgaP_AGAP008863
    XP_319605.4
930 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Protein kinase G oxidation is a major cause of injury during sepsis.
Rudyk O, et al. Proc Natl Acad Sci U S A 110, 9909-13 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DD_cGKI (cl17044)
  Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I.
CAP_ED (cl00047)
  effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
Pkinase_C (cl11395)
  Protein kinase C terminal domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Prkg1 includes H.sapiens PRKG1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 10 species)
Actinopterygii - bony fishes (11 transcripts, 5 species)
Ascidiacea - tunicates (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 1 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 10 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (5 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (4 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (3 transcripts, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (2 transcripts, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (20 transcripts, 15 species)
Liliopsida - monocots (8 transcripts, 8 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (2 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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