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HomoloGene:20559. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NDN,  H.sapiens
necdin, melanoma antigen (MAGE) family member
    NP_002478.1
321 aa
   NDN,  P.troglodytes
necdin homolog (mouse)
    XP_510257.2
321 aa
   NDN,  M.mulatta
necdin homolog (mouse)
    NP_001165573.1
321 aa
   NDN,  C.lupus
necdin homolog (mouse)
    XP_005618297.1
325 aa
   NDN,  B.taurus
necdin homolog (mouse)
    NP_001014982.1
325 aa
   Ndn,  M.musculus
necdin
    NP_035012.2
325 aa
   Ndn,  R.norvegicus
necdin, melanoma antigen (MAGE) family member
    NP_001008558.1
325 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Prader-Willi syndrome.



Publications
Articles associated with genes and sequences of this homology group.

Necdin controls proliferation of white adipocyte progenitor cells.
Fujiwara K, et al. PLoS One 7, e30948 (2012).
Necdin: a multi functional protein with potential tumor suppressor role?
Chapman EJ & Knowles MA. Mol Carcinog 48, 975-81 (2009).
[Regulation of neuronal development by the imprinted gene Necdin].
Yoshikawa K. No To Hattatsu 41, 214-8 (2009).
Necdin gene, respiratory disturbances and Prader-Willi syndrome.
Zanella S, et al. Adv Exp Med Biol 605, 159-64 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MAGE (pfam01454)
  MAGE family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ndn includes H.sapiens NDN and R.norvegicus Ndn.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)

 

 

 

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