Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:1359. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CDH5,  H.sapiens
cadherin 5, type 2 (vascular endothelium)
    NP_001786.2
784 aa
   CDH5,  P.troglodytes
cadherin 5, type 2 (vascular endothelium)
    XP_523383.3
784 aa
   CDH5,  M.mulatta
cadherin 5, type 2 (vascular endothelium)
    XP_001082641.1
785 aa
   CDH5,  C.lupus
cadherin 5, type 2 (vascular endothelium)
    XP_546894.2
772 aa
   CDH5,  B.taurus
cadherin 5, type 2 (vascular endothelium)
    NP_001001601.1
783 aa
   Cdh5,  M.musculus
cadherin 5
    NP_033998.2
784 aa
   Cdh5,  R.norvegicus
cadherin 5
    NP_001100877.1
776 aa
   CDH5,  G.gallus
cadherin 5, type 2 (vascular endothelium)
    NP_989558.1
773 aa
   cdh5,  X.tropicalis
cadherin 5, type 2 (vascular endothelium)
    XP_002933718.2
770 aa
   cdh5,  D.rerio
cadherin 5
    NP_001003983.1
767 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

VE-cadherin status as an indicator of microvascular permeability.
Monaghan-Benson E & Burridge K. Methods Mol Biol 1046, 335-42 (2013).
Vascular endothelial cadherin modulates renal interstitial fibrosis.
Yamaguchi I, et al. Nephron Exp Nephrol 120, e20-31 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Cadherin_C (pfam01049)
  Cadherin cytoplasmic region.
Cadherin_C (pfam01049)
  Cadherin cytoplasmic region.
CA_like (cl15786)
  Cadherin repeat-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cdh5 includes H.sapiens CDH5 and R.norvegicus Cdh5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 10 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

Write to the Help Desk