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HomoloGene:600. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   CSF2,  H.sapiens
colony stimulating factor 2 (granulocyte-macrophage)
144 aa
   CSF2,  P.troglodytes
colony stimulating factor 2 (granulocyte-macrophage)
144 aa
   CSF2,  M.mulatta
colony stimulating factor 2 (granulocyte-macrophage)
144 aa
   CSF2,  C.lupus
colony stimulating factor 2 (granulocyte-macrophage)
144 aa
   CSF2,  B.taurus
colony stimulating factor 2 (granulocyte-macrophage)
143 aa
   Csf2,  M.musculus
colony stimulating factor 2 (granulocyte-macrophage)
141 aa
   Csf2,  R.norvegicus
colony stimulating factor 2 (granulocyte-macrophage)
144 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Effect of alveolar epithelial cell plasticity on the regulation of GM-CSF expression.
Mir-Kasimov M, et al. Am J Physiol Lung Cell Mol Physiol 302, L504-11 (2012).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CSF2 (cl11465)
  Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is a member of the large family of polypeptide growth factors called cytokines. It stimulates a wide variety of hematopoietic and nonhematopoietic cell types via binding to members of the cytokine receptor family, mainly the GM-CSF receptor.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Csf2 includes H.sapiens CSF2 and R.norvegicus Csf2.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (9 transcripts, 8 species)

Coccidia - apicomplexans (1 transcript, 1 species)




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