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HomoloGene:7245. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   BDNF,  H.sapiens
brain-derived neurotrophic factor
    NP_001137282.1
329 aa
   BDNF,  P.troglodytes
brain-derived neurotrophic factor
    NP_001012443.1
247 aa
   BDNF,  M.mulatta
brain-derived neurotrophic factor
    XP_001089568.2
329 aa
   BDNF,  C.lupus
brain-derived neurotrophic factor
    NP_001002975.1
247 aa
   BDNF,  B.taurus
brain-derived neurotrophic factor
    NP_001040072.1
250 aa
   Bdnf,  M.musculus
brain derived neurotrophic factor
    NP_031566.4
257 aa
   Bdnf,  R.norvegicus
brain-derived neurotrophic factor
    NP_036645.2
257 aa
   BDNF,  G.gallus
brain-derived neurotrophic factor
    NP_001026787.1
246 aa
   bdnf,  X.tropicalis
brain-derived neurotrophic factor
    NP_001090767.1
247 aa
   bdnf,  D.rerio
brain-derived neurotrophic factor
    NP_571670.2
270 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Memory impairment, susceptibility to.
Obsessive-compulsive disorder, protection against.
Central hypoventilation syndrome, congenital.
Anorexia nervosa, susceptibility to.
Bulimia nervosa, age of onset of weight loss in.



Publications
Articles associated with genes and sequences of this homology group.

Small-molecule trkB agonists promote axon regeneration in cut peripheral nerves.
English AW, et al. Proc Natl Acad Sci U S A 110, 16217-22 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NGF (pfam00243)
  Nerve growth factor family.
NGF (cl02481)
  Nerve growth factor family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Bdnf includes H.sapiens BDNF and R.norvegicus Bdnf.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (7 transcripts, 7 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)

 

 

 

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