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HomoloGene:48460. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   EHMT2,  H.sapiens
euchromatic histone-lysine N-methyltransferase 2
1210 aa
   EHMT2,  P.troglodytes
euchromatic histone-lysine N-methyltransferase 2
1222 aa
   EHMT2,  M.mulatta
euchromatic histone-lysine N-methyltransferase 2
1068 aa
   EHMT2,  C.lupus
euchromatic histone-lysine N-methyltransferase 2
1267 aa
   EHMT2,  B.taurus
euchromatic histone-lysine N-methyltransferase 2
1211 aa
   Ehmt2,  M.musculus
euchromatic histone lysine N-methyltransferase 2
1263 aa
   Ehmt2,  R.norvegicus
euchromatic histone lysine N-methyltransferase 2
1263 aa
   ehmt2,  X.tropicalis
euchromatic histone-lysine N-methyltransferase 2
1150 aa
   ehmt2,  D.rerio
euchromatic histone-lysine N-methyltransferase 2
1173 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Epigenetic regulation of autophagy by the methyltransferase G9a.
Artal-Martinez de Narvajas A, et al. Mol Cell Biol 33, 3983-93 (2013).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ank (pfam00023)
  Ankyrin repeat.
Ank_2 (pfam12796)
  Ankyrin repeats (3 copies).
Pre-SET (pfam05033)
  Pre-SET motif.
ANK (cd00204)
  ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
Ank_2 (pfam12796)
  Ankyrin repeats (3 copies).
Ank_5 (cl02529)
  Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
SET (cl02566)
  SET domain.
Pre-SET (cl02622)
  Pre-SET motif.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ehmt2 includes H.sapiens EHMT2 and R.norvegicus Ehmt2.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (6 transcripts, 5 species)
Amphibia - amphibians (1 transcript, 1 species)

Insecta - insects (1 transcript, 1 species)

Hirudinida - segmented worms (1 transcript, 1 species)

Eudicotyledons - eudicots (1 transcript, 1 species)




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