Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:7861. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NFATC2,  H.sapiens
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    NP_775114.1
925 aa
   NFATC2,  P.troglodytes
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    XP_525356.2
925 aa
   NFATC2,  M.mulatta
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    XP_001099268.2
893 aa
   NFATC2,  C.lupus
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    XP_005635238.1
899 aa
   NFATC2,  B.taurus
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    XP_002692403.2
918 aa
   Nfatc2,  M.musculus
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
    NP_035029.2
927 aa
   Nfatc2,  R.norvegicus
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    NP_001101275.1
931 aa
   NFATC2,  G.gallus
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    XP_417509.3
927 aa
   nfatc2,  X.tropicalis
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    XP_002933215.2
900 aa
   LOC100333254,  D.rerio
nuclear factor of activated T-cells, cytoplasmic 2-like
    XP_003201273.2
894 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

NFATc2 is a potential therapeutic target in human melanoma.
Perotti V, et al. J Invest Dermatol 132, 2652-60 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RHD-n (cl08275)
  N-terminal sub-domain of the Rel homology domain (RHD).
RHD-n (cl08275)
  N-terminal sub-domain of the Rel homology domain (RHD).
IPT (cl15674)
  Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nfatc2 includes H.sapiens NFATC2 and R.norvegicus Nfatc2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 8 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Arachnida - arachnids (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

 

 

 

Write to the Help Desk