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HomoloGene:32507. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   MLXIPL,  H.sapiens
MLX interacting protein-like
852 aa
   MLXIPL,  P.troglodytes
MLX interacting protein-like
852 aa
   LOC720093,  M.mulatta
williams-Beuren syndrome chromosomal region 14 protein-like
387 aa
   MLXIPL,  C.lupus
MLX interacting protein-like
909 aa
   MLXIPL,  B.taurus
MLX interacting protein-like
856 aa
   Mlxipl,  M.musculus
MLX interacting protein-like
864 aa
   Mlxipl,  R.norvegicus
MLX interacting protein-like
865 aa
   LOC101882187,  D.rerio
carbohydrate-responsive element-binding protein-like
308 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Novel insights into ChREBP regulation and function.
Filhoulaud G, et al. Trends Endocrinol Metab 24, 257-68 (2013).
ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.
Metukuri MR, et al. Diabetes 61, 2004-15 (2012).
ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity.
Hurtado del Pozo C, et al. Biochim Biophys Acta 1811, 1194-200 (2011).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HLH (cl00081)
  Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
B_zip1 (cl02576)
  basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mlxipl includes H.sapiens MLXIPL.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (10 transcripts, 8 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)

Maxillopoda - crustaceans (1 transcript, 1 species)

Trematoda - flatworms (1 transcript, 1 species)

Polychaeta - segmented worms (1 transcript, 1 species)




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