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HomoloGene:5387. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ALG1,  H.sapiens
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
    NP_061982.3
464 aa
   ALG1,  P.troglodytes
asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae)
    XP_510796.2
464 aa
   LOC710713,  M.mulatta
chitobiosyldiphosphodolichol beta-mannosyltransferase-like
    XP_001099380.2
353 aa
   ALG1,  C.lupus
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
    XP_851486.1
464 aa
   ALG1,  B.taurus
asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae)
    NP_001192532.1
464 aa
   Alg1,  M.musculus
asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase)
    NP_663337.2
482 aa
   ALG1,  G.gallus
asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae)
    XP_414707.3
462 aa
   alg1,  X.tropicalis
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
    NP_001025606.1
375 aa
   alg1,  D.rerio
asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase)
    NP_956161.1
488 aa
   CG18012,  D.melanogaster
CG18012
    NP_650662.1
446 aa
   AgaP_AGAP003551,  A.gambiae
AgaP_AGAP003551
    XP_313298.3
440 aa
   T26A5.4,  C.elegans
T26A5.4
    NP_498420.2
491 aa
   ALG1,  S.cerevisiae
ALG1
    NP_009668.3
449 aa
   KLLA0B09405g,  K.lactis
KLLA0B09405g
    XP_451947.1
447 aa
   AGOS_ADL338C,  E.gossypii
AGOS_ADL338C
    NP_983757.2
471 aa
   alg1,  S.pombe
alg1
    NP_593186.1
424 aa
   MGG_10494,  M.oryzae
MGG_10494
    XP_003713398.1
456 aa
   NCU07261,  N.crassa
NCU07261
    XP_962115.1
456 aa
   AT1G16570,  A.thaliana
AT1G16570
    NP_173105.1
465 aa
   Os03g0180700,  O.sativa
Os03g0180700
    NP_001049165.1
473 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Congenital disorder of glycosylation, type Ik.



Publications
Articles associated with genes and sequences of this homology group.

Temperature-sensitive yeast mutants deficient in asparagine-linked glycosylation.
Huffaker TC & Robbins PW. J Biol Chem 257, 3203-10 (1982).
Yeast mutants deficient in protein glycosylation.
Huffaker TC & Robbins PW. Proc Natl Acad Sci U S A 80, 7466-70 (1983).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PLN02275 (PLN02275)
  transferase, transferring glycosyl groups.
Glycosyltransferase_GTB_type (cl10013)
  Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Alg1 includes H.sapiens ALG1 and R.norvegicus Alg1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (18 transcripts, 12 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (12 transcripts, 10 species)
Arachnida - arachnids (3 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (22 transcripts, 19 species)
Liliopsida - monocots (9 transcripts, 7 species)
Coniferopsida - conifers (3 transcripts, 3 species)
Bryopsida - mosses (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (2 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

 

 

 

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