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HomoloGene:37553. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   DAO,  H.sapiens
D-amino-acid oxidase
    NP_001908.3
347 aa
   DAO,  M.mulatta
D-amino-acid oxidase
    XP_001103664.1
347 aa
   DAO,  C.lupus
D-amino-acid oxidase
    XP_543443.2
347 aa
   DAO,  B.taurus
D-amino-acid oxidase
    NP_001193154.1
347 aa
   Dao,  M.musculus
D-amino acid oxidase
    NP_001273325.1
345 aa
   Dao,  R.norvegicus
D-amino-acid oxidase
    NP_446078.1
346 aa
   dao,  X.tropicalis
D-amino-acid oxidase
    NP_001090631.1
347 aa
   dao.1,  D.rerio
D-amino-acid oxidase, tandem duplicate 1
    NP_001028912.1
348 aa
   dao.2,  D.rerio
D-amino-acid oxidase, tandem duplicate 2
    NP_999897.1
348 aa
   dao.3,  D.rerio
D-amino-acid oxidase, tandem duplicate 3
    NP_991257.1
353 aa
   CG11236,  D.melanogaster
CG11236
    NP_609075.1
341 aa
   AgaP_AGAP001116,  A.gambiae
AgaP_AGAP001116
    XP_322047.5
350 aa
   KLLA0A08492g,  K.lactis
KLLA0A08492g
    XP_451375.1
373 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Schizophrenia.



Publications
Articles associated with genes and sequences of this homology group.

Structure-function relationships in human D-amino acid oxidase.
Sacchi S, et al. Amino Acids 43, 1833-50 (2012).
D-amino acid oxidase controls motoneuron degeneration through D-serine.
Sasabe J, et al. Proc Natl Acad Sci U S A 109, 627-32 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DAO (pfam01266)
  FAD dependent oxidoreductase.
DadA (COG0665)
  Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism].
Periplasmic_Binding_Protein_Type_1 (cl10011)
  Type 1 periplasmic binding fold superfamily.
DAO (pfam01266)
  FAD dependent oxidoreductase.
NAD_binding_8 (cl19134)
  NAD(P)-binding Rossmann-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Dao includes H.sapiens DAO and R.norvegicus Dao.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

 

 

 

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