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HomoloGene:55740. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   EZR,  H.sapiens
ezrin
    NP_003370.2
586 aa
   EZR,  P.troglodytes
ezrin
    XP_003311612.1
586 aa
   EZR,  M.mulatta
ezrin
    XP_002803901.1
554 aa
   EZR,  C.lupus
ezrin
    XP_541173.2
586 aa
   EZR,  B.taurus
ezrin
    NP_776642.1
581 aa
   Ezr,  M.musculus
ezrin
    NP_033536.2
586 aa
   Ezr,  R.norvegicus
ezrin
    NP_062230.1
586 aa
   EZR,  G.gallus
ezrin
    NP_990216.1
585 aa
   ezr,  X.tropicalis
ezrin
    NP_001025629.1
582 aa
   ezra,  D.rerio
ezrin a
    NP_001018326.1
595 aa
   ezrb,  D.rerio
ezrin b
    NP_001025456.1
583 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Interactome analysis reveals ezrin can adopt multiple conformational states.
Viswanatha R, et al. J Biol Chem 288, 35437-51 (2013).
Ezrin regulates the expression of Mrp2/Abcc2 and Mdr1/Abcb1 along the rat small intestinal tract.
Nakano T, et al. Am J Physiol Gastrointest Liver Physiol 305, G807-17 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FERM_M (pfam00373)
  FERM central domain.
ERM (pfam00769)
  Ezrin/radixin/moesin family.
FERM_N (pfam09379)
  FERM N-terminal domain.
FERM_M (pfam00373)
  FERM central domain.
ERM (pfam00769)
  Ezrin/radixin/moesin family.
FERM_N (pfam09379)
  FERM N-terminal domain.
PH-like (cl17171)
  Pleckstrin homology-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ezr includes H.sapiens EZR and R.norvegicus Ezr.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (21 transcripts, 14 species)
Actinopterygii - bony fishes (13 transcripts, 10 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

 

 

 

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