Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:31126. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SLC10A1,  H.sapiens
solute carrier family 10 (sodium/bile acid cotransporter), member 1
    NP_003040.1
349 aa
   SLC10A1,  P.troglodytes
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
    XP_510035.2
349 aa
   SLC10A1,  M.mulatta
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
    XP_001110268.1
349 aa
   SLC10A1,  C.lupus
solute carrier family 10 (sodium/bile acid cotransporter), member 1
    XP_537494.2
392 aa
   SLC10A1,  B.taurus
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
    NP_001039804.1
370 aa
   Slc10a1,  M.musculus
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
    NP_001171032.1
362 aa
   Slc10a1,  R.norvegicus
solute carrier family 10 (sodium/bile acid cotransporter), member 1
    NP_058743.1
362 aa
   LOC100489580,  X.tropicalis
sodium/bile acid cotransporter-like
    XP_002936944.2
346 aa
   slc10a1,  D.rerio
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
    XP_690745.4
343 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Cysteine 96 of Ntcp is responsible for NO-mediated inhibition of taurocholate uptake.
Ramasamy U, et al. Am J Physiol Gastrointest Liver Physiol 305, G513-9 (2013).
Nitric oxide-mediated inhibition of taurocholate uptake involves S-nitrosylation of NTCP.
Schonhoff CM, et al. Am J Physiol Gastrointest Liver Physiol 300, G364-70 (2011).
Protein kinase C induces endocytosis of the sodium taurocholate cotransporting polypeptide.
Stross C, et al. Am J Physiol Gastrointest Liver Physiol 299, G320-8 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SBF (pfam01758)
  Sodium Bile acid symporter family.
SBF (cl19217)
  Sodium Bile acid symporter family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slc10a1 includes H.sapiens SLC10A1 and R.norvegicus Slc10a1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (11 transcripts, 10 species)
Liliopsida - monocots (3 transcripts, 2 species)
Coniferopsida - conifers (1 transcript, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Chordata
Mammalia - mammals (11 transcripts, 11 species)
Actinopterygii - bony fishes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

 

 

 

Write to the Help Desk