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HomoloGene:12868. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CCM2,  H.sapiens
cerebral cavernous malformation 2
    NP_001025006.1
465 aa
   CCM2,  P.troglodytes
cerebral cavernous malformation 2
    XP_519079.3
444 aa
   CCM2,  M.mulatta
cerebral cavernous malformation 2
    XP_002803328.1
466 aa
   LOC100856167,  C.lupus
malcavernin-like
    XP_005629627.1
462 aa
   CCM2,  B.taurus
cerebral cavernous malformation 2
    NP_001180140.1
476 aa
   Ccm2,  M.musculus
cerebral cavernous malformation 2
    NP_666126.1
453 aa
   Ccm2,  R.norvegicus
cerebral cavernous malformation 2
    NP_001119747.1
453 aa
   CCM2,  G.gallus
cerebral cavernous malformation 2
    NP_001184073.1
453 aa
   ccm2,  X.tropicalis
cerebral cavernous malformation 2
    XP_002941370.2
458 aa
   ccm2,  D.rerio
cerebral cavernous malformation 2
    NP_001002315.1
455 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Cerebral cavernous malformations-2.



Publications
Articles associated with genes and sequences of this homology group.

CCM2 expression during prenatal development and adult human neocortex.
Tanriover G, et al. Int J Dev Neurosci 29, 509-14 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PH-like (cl00273)
  Pleckstrin homology-like domain.
harmonin_N_like (cl11968)
  N-terminal protein-binding module of harmonin and similar domains, also known as HHD (harmonin homology domain).
PH-like (cl17171)
  Pleckstrin homology-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ccm2 includes H.sapiens CCM2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 12 species)
Actinopterygii - bony fishes (9 transcripts, 7 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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